DIALS: Diffraction Integration for Advanced Light Sources¶
X-ray crystallography for structural biology has benefited greatly from a number of advances in recent years including high performance pixel array detectors, new beamlines capable of delivering micron and sub-micron focus and new light sources such as XFELs. The DIALS project is a collaborative endeavour to develop new diffraction integration software to meet the data analysis requirements presented by these recent advances. There are three end goals: to develop an extensible framework for the development of algorithms to analyse X-ray diffraction data; the implementation of algorithms within this framework and finally a set of user facing tools using these algorithms to allow integration of data from diffraction experiments on synchrotron and free electron sources.
Contact¶
For feature requests, bug reports or any other information, please contact the DIALS developers at dials-support@lists.sourceforge.net, or post an issue.
Citing DIALS¶
Researchers using DIALS to process their data should cite the DIALS publication:
DIALS: implementation and evaluation of a new integration package. Winter G, Waterman DG, Parkhurst JM, Brewster AS, Gildea RJ, Gerstel M, Fuentes-Montero L, Vollmar M, Michels-Clark T, Young ID, Sauter NK, Evans G (2018). Acta Crystallogr D Struct Biol 74, 85-97
To acknowledge direct support from the DIALS Resource, such as when Resource staff assist with data collection or processing, or to acknowledge DIALS software integration at a facility or instrument, please acknowledge NiH grant R24GM154040.
Funding¶
DIALS development at Diamond Light Source is performed by employees of Diamond Light Source, and STFC via CCP4.
We are supported by funding from Wellcome for grant 218270/Z/19/Z: DIALS: making serial crystallography data analysis accessible for biomedical researchers.
DIALS development at Lawrence Berkeley National Laboratory is supported by National Institutes of Health / National Institute of General Medical Sciences grant R24GM154040.
DIALS is an NIH NIGMS US National Resource with the goal of supporting both users and facilities in using DIALS to analyse their diffraction data. Learn more.
Work at LBNL is performed under Department of Energy contract DE-AC02-05CH11231.
